Block of 5-HT2 Receptors Enhances Hippocampal Long-Term Potentiation
نویسندگان
چکیده
The effect of endogenous serotonin on long-term potentiating (LTP) in region CA1 was studied by blocking 5-HT2 receptors with ketanserin in rat hippocampal slices. Such a block significantly enhanced long-term potentiation of the CA1 population spike induced by high frequency stimulation of the schaffer collateral/ commissural pathway. This implies that serotonin acts on 5-HT2 receptors in CA1 to repress long-term potentiation. Iran. Biomed. J. 2: 129-131, 1998
منابع مشابه
Block of 5-HT2 Receptors Enhances Hippocampal Long-Term Potentiation
The effect of endogenous serotonin on long-term potentiation (LTP) in region CAI was studied by blocking 5-HT2 receptors with ketanserin in rat hippocampal slices. Such a block significantly en-hanced long-term potentiation of the CAI population spike induced by high frequency stimulation of the schaffer collateral/ commissural pathway. This implies that serotonin acts on 5-HT2 receptors in CAI...
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تاریخ انتشار 2013